Oral or intravenous antidote for paracetamol overdose
نویسندگان
چکیده
منابع مشابه
Interventions for paracetamol (acetaminophen) overdose.
BACKGROUND Paracetamol (acetaminophen) is the most widely used non-prescription analgesic in the world. Paracetamol is commonly taken in overdose either deliberately or unintentionally. In high-income countries, paracetamol toxicity is a common cause of acute liver injury. There are various interventions to treat paracetamol poisoning, depending on the clinical status of the person. These inter...
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OBJECTIVE To evaluate the role of liver transplantation after paracetamol overdose. DESIGN Prospective study of consecutive candidates for transplantation and performance of transplantation over 18 months. SETTING Liver unit, King's College Hospital, London. MAIN OUTCOME MEASURES Fulfilment of indicators of poor prognosis, selection for transplantation, transplantation, survival. RESULT...
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Two patients with severe thrombocytopenia after paracetamol overdose are described. The platelet count was lowest two days after the overdose. Neither leucopenia nor anaemia occurred.
متن کاملOral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
BACKGROUND Paracetamol formulations provide effective analgesia after surgery [Duggan ST, Scott LJ. Intravenous paracetamol (acetominophen). Drugs 2009; 69: 101-13; Toms L, McQuay HJ, Derry S, Moore RA. Single dose oral paracetamol (acetaminophen) for postoperative pain in adults. Cochrane Database Syst Rev 2008: CD004602]. I.V. paracetamol is superior to oral for pain rescue (Jarde O, Boccard ...
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The first oral overdose of paracetamol in a neonate is reported. A 55 day old neonate, born 29 weeks premature, was accidentally given 136 mg/kg paracetamol. Treatment was with activated charcoal, supportive care, and N-acetylcysteine. There was no biochemical evidence of hepatotoxicity, and no long term sequelae. After modelling of the data, the following pharmacokinetic variables were calcula...
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ژورنال
عنوان ژورنال: Emergency Medicine Journal
سال: 2002
ISSN: 1472-0205,1472-0213
DOI: 10.1136/emj.19.3.247-a